进行性系统性硬皮病（progressive systemic scleroderma）：进行性系统性硬皮病属于侵犯全身脏器，全身皮肤发硬为特征的结缔组织疾病。诊断要点：有两个主要的临床类型。
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Esophageal motility problems can occur in patients with progressive systemic sclerosis (scleroderma) because the submucosa becomes fibrotic.
系统性硬化(硬皮病)病人食管蠕动障碍，因为黏膜下层纤维化。
Scleroderma(or progressive systemic sclerosis):Chronic disease that hardens the skin and fixes it to underlying structures.
硬皮病（亦称进行性全身硬化症）：一种使皮肤变硬并固着于皮下结构的慢性皮肤病。
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