...氨基酸排列顺序,从理论上预测相应的空间结构就成 了分子生物学中的一个重要问题,即 蛋白质折叠问题 ( protein folding problem )。然而,对大多数蛋白质构象 机理的阐明来说蛋白质空间构象预 目前,有关蛋白质结构与临床疾病的关系研究倍受人们瞩目。
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Enumerating the allowed sequences for a given fold is known as the 'inverse protein folding problem'.
为一个给定的折叠列举允许的序列被称为逆蛋白质折叠问题。
Protein structure prediction problem is to predict the dimensional folding configurations from its amino acid sequence.
蛋白质构形预测问题就是根据组成蛋白质的氨基酸序列来预测其空间折叠结构。
Recently it applied on the problem of protein folding and 3d structure prediction using these methods are then reviewed. The effect and feature of these methods are also analyzed and compared.
对国内外近年来应用这些方法在蛋白质3d结构预测及折叠的研究工作进行了回顾,并分析、比较了这几种方法的效果和特点。
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