...巽菌站宓诬鸾嗟彡梁圭跞皙钢漶恍喧共禀莼谒婪鞘嚣陔兔铳珊数雨亲芏嘱虽免逝 E 1 —— 丙酮酸脱氢酶(pyruvate dehydrogenase PDH)。催化丙酮酸的脱羧及脱氢，形成二碳单位乙酰 基。
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PDH pyruvate dehydrogenase 丙酮酸脱氢酶
Hypoxia can directly induce pyruvate dehydrogenase kinase 1 (PDHK1) expression, which results in inactivation of PDH and the TCA cycle and subsequent suppression of metabolism (4).
低氧条件会直接诱导丙酮酸脱氢酶激酶1 (PDHK1)的表达，它的表达会抑制pdh的活性和TCA循环，从而抑制了随后的代谢通路(4)。
Pyruvate generated from glycolysis is converted to acetyl-CoA by pyruvate dehydrogenase (PDH) under normoxia (1-3).
糖酵解产生的丙酮酸在正常条件下被丙酮酸脱氢酶(PDH)转化成乙酰辅酶a (1 - 3)。
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