He had been running uphill a long way.

他向上坡跑了很长的一段路。

《柯林斯英汉双解大词典》

I never ran uphill in 2008, so I decided that I shouldn't practice running uphill in my training.

在2008年，我从没有在上山时跑过，所以我觉得没有必要训练向山上跑。

youdao

Uphill running forces you to drive your arms harder than you do when running on flat ground, so you'll improve your upper body strength.

使您的上身有劲：跑坡道迫使您摆臂比跑平地时更加用力，因此，您的上身力量可以提高。

youdao

Rick Santorum - the incumbent senator of two terms -really is running an uphill race, but he's a great campaigner and he has money.

NPR: Democrats on Offense as Elections Approach

This is both harder and more of an adrenaline rush than it seems, because the sled likes to tip over and keeping it from doing so involves a lot of squatting and leaning, while going uphill means getting your weight off the sled and running behind, like pushing a grocery cart, to help the dogs.

FORBES: Try Dog Sledding - It's Awesome Winter Fun!