其次是重要不良事件（Significant Adverse Event）即在用药过程中发生的不良事件和血液学或其他实验室检查明显异常，并且这些不良事件和血液学或其他实验室检查明显异常必须采取针...
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FDA's review of adverse event reports found cases of significant weight gain and edema-warning signs of heart failure.
FDA不良反应调查报告发现明显体重增加和水肿病例提示心衰的体征。
There was no significant difference in the frequency of adverse event and serious laboratory abnormalities between entacapone and placebo groups.
不良事件的发生率与安慰剂组相比差异无显著意义。
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