Believing yourself to be in the wrong job can be soul-destroying.

认为自己干的工作不适合自己令人心灰意冷。

《柯林斯英汉双解大词典》

"I'm sure at the time people thought the piano was destroying the soul of our music," Chordia says.

“我相信当时人们认为钢琴是在破坏我们音乐的灵魂，”Chordia说。

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For at least some of those with soul-destroying morning commutes, liberation may indeed be at hand.

至少对于那些乘公交上班的心灵受到破坏的人来说，即将得到解放。

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If the mind is like the harmony of the body, then maybe you could destroy the mind, the soul by destroying the body on which the mind depends.

如果精神像是身体的和声，那也许你可以通过毁灭,精神依靠的肉体来毁灭,精神和灵魂。

耶鲁公开课 - 死亡课程节选

I'll go to my grave with this pain, it was soul destroying, and the pain will never leave me.

CNN: STORY HIGHLIGHTS

Churchwarden Mollie Pascoe said the latest theft was "soul destroying".

BBC: Lead laid on St Stythians' church roof stolen hours later

"With youth employment reaching the one million mark, funding opportunities for skills development is surely better than the soul destroying experience of sitting at home, watching Jeremy Kyle, on the dole, " he said.

BBC: Graduates to get gap-year money