Conclusion: The spatial reference memory and spatial working memory are reliable methods to examine AD model.

结论：空间参考记忆和空间工作记忆是检测ad模型的可靠方法。

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Objective: To explore the reliability of Alzheimer's disease, AD model in rats with spatial reference memory and spatial working memory.

目的：损伤大鼠双侧基底核形成阿尔茨海默病(AD)模型，用空间参考记忆和空间工作记忆共同检测该模型的可靠性。

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Results: The spatial reference memory and spatial working memory of the model group declined more significantly than those of the young and senile control groups , P<0.01).

结果：模型组与青年组、老年组相比，空间参考记忆和空间工作记忆均明显下降（P<0.01）。

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