Studies in recent years have found that cortical spreading depression (CSD) may be one of the important mechanisms for the cause of migraine.

近年来的研究发现，皮质扩散抑制(CSD)可能是偏头痛发病的重要机制之一。

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Its pathogenesis is still not completely clarified, animal models are established on the basis of trigeminovascular theory, cortical spreading depression theory and neurovascular theory.

其发病机制至今尚未完全明了，动物模型基于三叉神经血管学说、皮层扩散抑制学说和血管学说等理论而建立。

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This wave known as "cortical spreading depression" activates nerve cells as it goes, and the symptoms sufferers report typically correspond to the area of the brain the wave is passing over.

WSJ: Stopping a Migraine Before It Starts