AIM: To investigate the role of the activation of hepatic stellate cells in small-for-size graft injury in a rat liver transplantation model.

目的：在大鼠小肝移植模型的基础上，检测大鼠小肝移植中肝星状细胞的激活在供肝损伤中所起的作用。

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This paper briefly reviews the hepatic stellate cells (HSC) activation and proliferation-related signal transduction pathway and explores the role in the pathogenesis of liver fibrosis.

本综述以肝星状细胞激活与增殖相关信号转导通路为中心，探讨其在肝纤维化发病作用方面的作用机制。

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The manipulation of the activation and proliferation of hepatic stellate cells and the process of liver fibrosis inversion are the key in anti-liver-fibrosis researches.

控制肝星状细胞的激活和增殖并逆肝纤维化的进程是抗肝纤维化研究的重点之一。

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