Objective to investigate the expression of connective tissue growth factor (CTGF) in the kidney of STZ induced diabetic rats and its relationship with the early renal hypertrophy.

目的：研究结缔组织生长因子(CTGF)在链脲佐菌素(STZ)诱导的糖尿病大鼠肾脏中的表达及其与肾小球肥大的关系。

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Results: Rubusoside could reduce the level of serum glucose significantly, enhance the ability of anti oxidation and stimulate the secretion of insulin in STZ induced diabetic rats.

结果：甜茶素提取物能极显著地降低STZ致高血糖大鼠血糖，增强其抗氧化能力，同时能刺激胰岛素的分泌。

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The diabetic rats models were induced by the single injection of streptozotocin (STZ) via coccygeal vein.

由尾静脉单次注射链脲佐菌素(STZ)，造成糖尿病大鼠模型。

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