With the thorough research of tumor mechanism, drugs acting on cell signal transduction pathway began to attract attention of researchers as an important target for anticancer drug development.

随着对肿瘤发生机制研究的深入，作用于细胞信号转导通路的药物开始引起研究者的关注，成为抗肿瘤药物研发的重要靶点之一。

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It is an important biological target in the drug screening and drug designing. Lots of anticancer drugs and antiviral drugs had effects on DNA.

对DNA的研究是生命科学研究中一个极其重要的方面，在药物筛选和药物设计中它是重要的作用靶点。

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Drug resistance and disease progression have been observed all for anticancer drugs that target specific genetic alterations.

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