But it can take a long time for the right mutation to occur, especially if there is a very small target, like the region of DNA that controls a gene.

但要得到最合适的变异基因，耗费的时间会非常长，尤其是所要达到目标非常小时，如DNA中用来控制别的基因的区域部分，将是一项旷日持久的工程。

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Unlike a genetic mutation that changes the function or activity of a gene, which can be inhibited by a well-tailored drug, loss of a gene leaves nothing for the drug to target.

不同的基因突变改变了功能或活动的一个基因，它可以抑制一种非常合适的药物，失去了基因树叶什么药物目标。

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The discovery could lead to development of drugs that target the defective gene, said the researchers at Duke University Medical Center who discovered the mutation.

杜克大学医学中心的研究人员声称，这项发现将带来药物的变革以针对该致病基因。

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