Objective: to investigate the changes of first phase insulin secretion in first degree relatives of type 2 diabetic family with normal glucose tolerance.
目的：探讨2型糖尿病家系非糖尿病一级亲属在糖耐量正常时胰岛素第一时相分泌情况。
Its main characteristic is the loss of first-phase insulin response to glucose, with gradual impairment of also second-phase or overall insulin secretion.
其主要特征是对葡萄糖反应的胰岛素释放第一相丧失，随之而来的是逐渐加重的第二相胰岛素和总胰岛素分泌的受损。
AIM: to clarify the relationship of serum uric acid and insulin resistance with first-phase islet secretion in hyperuricemic patients, and the factors that influence them.
目的：明确发生高尿酸血症患者胰岛素抵抗和胰岛第一分泌时相及其影响因素。
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