The efforts we have made seem to be of no use and we feel very disappointed.

我们做出了很多努力似乎是毫无用处的，我们感到非常失望。

youdao

When paper turns out to be of no use, the waste paper is collected and retreated in the recycling factory before being put into use again.

当纸是没有用的，收集废纸和撤退前的回收工厂再次被投入使用。

youdao

Once I get there, there would be no daily list of activities, sightseeing trips, television or business centers I might use to "check-in" at work.

我一旦到了那里，就不会有每天的活动清单、观光旅行、看电视或在工作时“签到”的商业中心。

youdao

After Senate approval of his treaty with Lord Ashburton, Webster decided that he could be of no more real use to the administration.

VOA: special.2009.02.05

So, if language seems exhausted because it's always preceding you, everything has always already been said, there's no new plot to be had, the world is full of stock phrases, how do you use them to embody an experience that seems fresh to you?

所以，如果因语言，在你之前就存在，而它就显得枯竭，如果一切都已经被说过，如果已没有新的情节可供创造，如果世界一直充满陈腔旧调，你如何能够用它们,呈现出一个崭新的体验？

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In light of this it is clear that Fatah can be of no use to anyone any longer.

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This seems to be a parsimonious explanation as there was no evidence of contamination prior to the use of these cell lines.

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Her cancer, she says, has spread so widely, touching her brain and liver that Avastin would no longer be of use to her.

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