Clozapine, marketed in Australia since 1993, is an effective antipsychotic for the management of treatment-resistant schizophrenia.

氯氮平，自从1993年在澳大利亚上市以来，一直作为一种有效的抗。

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These discoveries may have clinical implications for the approximately 33 percent of schizophrenia patients whose auditory hallucinations are resistant to treatment, Cachia told Psychiatric News.

卡夏告诉《精神病新闻》，这些发现对临床产生一定的意义，介于33%的具有幻听的精神分裂症患者对过去治疗阻抗。

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In this article, the author reviewed biological factors, drug treatment and non - drug treatment of the treatment resistant schizophrenia, and provided theoretical guidance for clinical treatment.

综述了难治性精神分裂症的生物学因素、药物治疗和非药物治疗方面的进展，为临床治疗提供理论指导。

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