实验采用经典的不确定预期的温和应激模型(unpredictable chronic mild stress, UCMS)诱导大鼠出现抑郁情绪,采用糖水偏好测试、旷场测试以及高架十字迷宫测试评价动物的情绪行为,并通过自发痛...
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chronic unpredictable mild stress 抑郁症 ; 尾壳核 ; 温和应激 ; 性应激
Chronic unpredictable mild stress model 慢性轻度不可预见应激抑郁模型
Conclusion It is an ideal method for establishing the animal model of post-encephalorrhagia depression to give chronic unpredictable mild stress to rats on the basis of cerebral hemorrhage.
结论在脑出血的基础上给予慢性不可预见的温和应激,能建立较理想的脑出血后抑郁动物模型。
METHODS: (1) The chronic stressed depression rats were established by chronic unpredictable mild stress and separation after 21 days.
方法:(1) 动物模型:连续21天慢性轻度不可预见性应激配合孤养方法建立大鼠抑郁模型。
The rat Dysthymic disorder model was produced by separation and chronic unpredictable mild stress.
应用分养和长期不可预见性中等强度应激造成大鼠恶劣心境障碍模型。
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