Objective:To optimize the extraction process of Bushen Tongbi Granuls.Methods: Using orthogonal design method,to apply extract yield of Rhizoma Coptis and the extract amount of berberine hydrochloride as observing indexes,to measure the content of dl-tetrahydropalmatine with HPLC.Results:The optimum extraction process was as follows,adding 8 times of 50%alcohol into coptis meal,refluxing and extracting for 2 times,one hour every time.Conclusion: This optimized process is simple,stable and efficient.
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Using orthogonal design method, the optimum reaction conditions were obtained.
通过正交实验得出最佳反应条件。
Using orthogonal design method, the immuno pharmacological effects of Buzhong Yiqi Decoction were studied.
采用正交设计法，对补中益气汤中药味的免疫药理效应进行析因研究。
Using orthogonal design method, adopting L9 34 table, to research the synthesis of N-acetyl-L-leucine, for improving the productive rate.
采用正交设计法，选择L9（34）表，研究N-乙酰-L-亮氨酸的合成，提高反应得率。
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