Woe betide anyone who got in his way.

谁妨碍了他，谁就会倒霉。

《柯林斯英汉双解大词典》

Woe betide anyone who gets in her way!

谁挡住她的路谁就会遭殃！

《牛津词典》

Woe betide the lazy fellow!

这懒家伙有祸了！

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If the party members keep their vote, woe betide the candidate who favoured their disenfranchisement.

ECONOMIST: The Tory leadership

But woe betide the country if ever-more-draconian measures became Mr Putin's only way of staving off ever-growing public discontent.

ECONOMIST: The Kremlin's control freak | The

Nuts are generally good accompaniments to most aperitifs, but woe betide the wine lover who attempts to pair dry roasted peanuts with wine.

WSJ: Will Lyons on Wine: Pairings for Those Salad Days | Best Wines for Vegetarian Dishes