目前染色体病的 PGD 方法主要采用荧光原位杂交 (FISH fluorescence in situ hybridization)技术,但由于探针成本较 高,多数生殖中心仅将形成正常配子几率较高的非同源罗氏易位 携带者列为PGD 适应症之一。
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Objective To explore the differences between radiation-induced translocation and dicentric chromosome aberrations detected by multicolor fluorescence in situ hybridization (M-FISH) method.
目的探讨用多色荧光原位杂交(M FISH)技术检测的易位和双着丝粒染色体畸变的差异。
Objective: To establish the method of aneuploidy detection in human oocytes by multicolor fluorescence in-situ hybridization (M-FISH).
目的建立多色荧光原位杂交技术检测人卵细胞染色体非整倍体的方法。
Objective To investigate the value of multiplex fluorescence in situ hybridization (M-FISH) in the detection of complex chromosomal abnormalities (CCAs) of chronic lymphocytic leukemia (CLL).
目的探讨多重荧光原位杂交(M - FISH)技术检测慢性淋巴细胞白血病(CLL)复杂核型异常(CCA)的价值。
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