Methods and results:Through acylation, Friedel Crafts reaction, reduction, hydrolysis, condensation and oxidation, the title compound was prepared with a total yield of 50.7%.

方法：以庚二酸单乙酯为原料，经酰氯化、傅克酰化、还原、水解、缩合及氧化反应合成塞曲司特。 结果：塞曲司特的总产率为5 0 .7%。

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METHODS: The title compounds were synthesized by acylation of twelve acyl chlorides and two intermediates prepared by Friedel Crafts reaction, lengthening of carbon chain, hydrolysis and cyclization;

方法：通过付克反应、碳链延长、水解和环合反应得到两个关键中间体，然后通过酰化反应制得各种酰胺化合物；

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The key steps, Friedel-Crafts reaction and Fremy's salt oxidation, were improved on the basis of original literature.

关键步骤弗-克反应和弗瑞麦氏盐氧化反应均在原文献的基础上作了相应的改进。

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