AIM to investigate the inhibitory effect of local perfusion of recombinant tissue factor pathway inhibitor protein on intima hyperplasia in atherosclerotic arteries after balloon stripping in rabbits.
目的：探讨兔髂动脉球囊剥脱术后局部灌注重组组织因子途径抑制物蛋白对血管内膜增生的抑制作用。
Intimal hyperplasia is the result of proliferation and migration of host arterial smooth muscle cell, which passes through the anastomosis to the intima of the vein graft.
内膜增殖是宿主动脉平滑肌细胞增殖，通过吻合口迁移至静脉内膜并增殖的结果。
Higher levels of FIB, CRP and LDL maybe the major high risk factors that lead to intima hyperplasia and artificial graft obliteration.
纤维蛋白原、低密度脂蛋白增高可能是导致吻合口内膜增生、人工血管闭塞的重要高危因素。
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