应用荧光实时定量RT．PCR法研究 瘢痕疙瘩成纤维细胞（keloid fibroblasts，KFs）中 TGF一，诱导靶基因纤溶酶原激活物抑制剂．1（plas． minogen activator ...
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...疙瘩 成纤维细胞生长 实验 DNA合成代谢 细胞增殖 【文 摘】目的 探讨野生型p16基因对人瘢痕疙瘩成纤维细胞(keloid fibroblasts，KFb)生长增殖及DNA合成代谢的影响。
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human keloid fibroblasts 人瘢痕疙瘩成纤维细胞
keloid-derived fibroblasts 瘢痕疙瘩成纤维细胞
keloid derived fibroblasts 瘢痕疙瘩成纤维细胞
Methods: keloid fibroblasts were isolated from fresh keloid tissue and cultured.
方法取新鲜瘢痕疙瘩组织，体外培养瘢痕成纤维细胞。
Conclusion P53 can obviously inhibit MMP1 and MMP3 expression in human keloid fibroblasts.
结论P 53蛋白能够抑制人瘢痕疙瘩成纤维细胞MMP1、MMP3蛋白的表达。
Conclusion: P53 protein significantly inhibits telomerase activity in human keloid fibroblasts.
结论：P 53蛋白能够抑制人瘢痕疙瘩成纤维细胞端粒酶活性。
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