At the end of the week, the men, whose mean weight starting out was 105 kilograms, had lost on average about 1.5 kg, the researchers report 4 February in Obesity.

一周之后，这些人的平均体重在105千克的基础上减掉了1.5千克，研究者将结果报告于2月4日的《肥胖》杂志。

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Peter has come to the end of his tether, he owed the bank a lot of money and lost his job last week.

彼得已经到了日暮途穷的地步。他欠银行一大行钱，又正在上个星期丢了劳动。

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At the end of a week they had lost all hope.

过了一星期，他们已是任何希看都没有了。

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If these devastating cuts in the sequester go into effect at the end of this week, three-quarters of a million jobs will be lost.

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