Objective to investigate the effects of oxidized low-density lipoprotein receptor 1 (LOX-1) on secretion of adhesive molecules mediated by ox-LDL in human umbilical endothelial cells (HUVECs).
目的探讨血凝素样氧化低密度脂蛋白受体1 (LOX - 1)在氧化低密度脂蛋白(ox - LDL)诱导血管内皮细胞粘附分子表达中的作用。
Early glycated low density lipoprotein (LDL) was not recognized by this receptor. AGEP BSA elevated cytosolic free calcium in a concentration dependent manner.
通过该受体介导,平滑肌细胞可内化、代谢AGEP.AGEP使胞浆游离钙呈浓度依赖性升高;
For instance, familial hypercholesterolemia (FH) typically results from mutations in LDLR encoding the low-density lipoprotein (LDL) receptor.
例如,家族性血胆脂醇过多症(FH)通常起源于编码低密度脂蛋白(LDL)受体的LDLR突变。
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