We are profoundly affected by what happens to us in childhood.

童年发生的事深深地影响着我们。

《牛津词典》

She is now profoundly deaf.

她现在几乎一点声音都听不到了。

《柯林斯英汉双解大词典》

This has profoundly affected my life.

这已极大地影响了我的生活。

《柯林斯英汉双解大词典》

"I firmly believe it is in Iran's interest not to develop nuclear weapons, because it would trigger a nuclear arms race in the Middle East and be profoundly destabilizing in all sorts of ways."

VOA: special.2009.05.23

While he's almost universally acclaimed as a profoundly important intellectual figure, he's also the object of considerable dislike.

他被公认为,极为重要的知识分子，但同时，他也成为了别人唾弃的对象。

耶鲁公开课 - 心理学导论课程节选

But there's something else that needs to be purged, and the poem recognizes that even more profoundly.

但还有其他一些事情需要被净化，诗歌更深刻的体现了这一点。

耶鲁公开课 - 弥尔顿课程节选

Traditional attitudes are being profoundly shaken by today's climate - and that could be for the better.

BBC: Greece's young: Dreams on hold as fight for jobs looms

By contrast, I found the sight of a haul of smuggled tusks in Bangkok Airport profoundly depressing.

BBC: Why such a fuss about extinction?

Difficult emotional journeys are beautifully rendered in "Far From Heaven, " and the musical is profoundly effective.

WSJ: Review: 'Far From Heaven' pretty close to heavenly