家族性和特发性肺动脉高压的遗传学研究进展郭英华 何建国 程显声 肺动脉高压（pulmonary artery hypertension PAH）是不同病因导致的、以肺动脉压力和肺血管阻力升高为特点的一组病理生理综合征。
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Pulmonary artery hypertension (PAH) is a combination of factors caused abnormal pulmonary hemodynamics. Pulmonary vascular resistance (PVR) progressive as clinical features of PAH.
肺动脉高压(PAH)是多种因素引起的肺血流动力学异常，以肺血管阻力进行性升高为临床特征的一组疾病。
OBJECTIVE: To study pharmacological mechanism of bosentan for treatment of pulmonary artery hypertension (PAH) and evaluate its clinical efficacy and the safety.
目的：探讨波生坦治疗肺动脉高压的药理机制，并评价其临床疗效和用药安全性。
Objective: Our aim was to study the levels of atrial natriuretic peptide (ANP) and pulmonary perfusion imaging in determining of pulmonary artery hypertension (PAH).
目的：探讨血浆心钠素含量和肺灌注显像判定肺动脉高压的程度及其意义。
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