AIM: To study the expression of predicted B cell epitope peptide in S2 subunit of SARS coronavirus spike protein in E. coli and its mimic antigenicity to S2 protein.

目的： 研究预测的SARS冠状病毒刺突蛋白S2亚基B细胞表位肽在大肠杆菌中的表达及其模拟S2蛋白的抗原性。

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Conclusions S2-protein from SARS coronavirus inhibits the chloride channel function in A549 cells, and both PKC and P38 are not involved in mediating this modulation.

结论SARS冠状病毒S2蛋白能抑制A549细胞氯通道的功能活动，PKC和P 38可能不参与S2蛋白对通道电流的抑制作用。

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To construct a clone p-SARS-S containing SARS coronavirus s gene fragment as the positive control of RT-PCR detect methods, which can build the basis for the expression of the gene.

构建SARS冠状病毒S基因序列克隆p - SARS - S，作为自行设计、建立的RT - p CR检测方法的阳性对照，并为该基因的表达奠定基础。

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The SARS coronavirus appears to be different from all other known coronaviruses, including animal ones.

FORBES: Magazine Article

In 2002 an outbreak of the Sars coronavirus killed about 800 people after it spread from Hong Kong to more than 30 countries around the world.

BBC: New coronavirus: May be 'bat bug'

"The 'super-spreading' events, in which one person infects several dozen people at a time (as was seen with SARS coronavirus), do not seem to be happening with this coronavirus" said Prof Peter Openshaw, Director of the Centre for Respiratory Infection, Imperial College London.

BBC: Threat from novel coronavirus 'remains low'