...医药卫生期刊奖 - Powered by SupeSite 关键词] 马钱子；普通粉；超微粉；LD50；ED50；TI [gap=826]Key words] Semen strychni ; Ordinary powder; Ultra micro powder; LD50; ED50; TI ..
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Nux Vomica Semen Strychni 马钱子 ; 马钱子粉末 ; 麦冬粉末
Semen Strychni Pulveratum 马钱子粉
fermented Semen strychni 马钱子发酵物
Semen Strychni Ignatii Luzon Poisonnut 吕宋果
Strychni Semen 马钱子
Methods:1. The protect effect of Semen Strychni on knee OA in rabbit was observed in vivi.
方法：1．通过在体实验观察马钱子对兔膝骨关节炎的保护作用。
参考来源 - 马钱子对骨关节炎中软骨细胞凋亡与增殖的影响The method is accurate and reproducible,providing a new reference for quality control of Semen Strychni.
该研究方法为马钱子药材的质量控制提供了参考。
参考来源 - 马钱子的炮制工艺及HPLC指纹图谱的研究·2,447,543篇论文数据，部分数据来源于NoteExpress
ResultsAcute toxic manifestations of Shufeng Huoluo pills were twitch, entasia, which resemble acute toxic symptoms of Semen Strychni.
结果含马钱子的疏风活络片的主要急性毒性表现为抽搐强直性痉挛，与马钱子急性中毒症状相似。
Conclusion Semen Strychni and its processed products of Jiangxi methods and innovated methods can lower the toxicity and improve the safety of clinical use.
结论江西法及其改良法炮制的马钱子比其砂烫法和油炸法更易降低毒性，使其安全范围增大，从而提高其临床用药的安全性。
It has been called in question on clinical safety, even not accepted by international market, due to toxical Semen Strychni as monarch drug which often induce adverse reaction.
但因其君药马钱子毒性较大，临床常有不良反应报道，从而影响该药的临床安全使用及国际准入。
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