The bigger issue is that the FDA's problem-ridden Adverse Event Reporting System isn't a systematic measure of how often drugs really cause side effects.
更大的问题是,受问题支配的FDA的不良反应事件报告系统不能系统的衡量药品引起的真实副作用的多少。
One patient relapsed; the adverse events were described as "mild" and not a result of the combination therapy, they were known effects of the individual drugs.
一个病人复发;笔者称此疗法副作用轻微并不是联合疗法结果,而是单独用药的已知副作用。
They also note: "Low-dose therapy has the advantage of reducing adverse effects that… are strongly dose related… Using more than two drugs in combination also would increase efficacy".
他们还写道:“低剂量的优势还在于可以减少副作用…这是与剂量有关的…两种以上药物的联合应用有助增加药效。”
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