电压依赖性钠离子通道(Voltage-gated sodium channels, VGSCs)在脑兴奋过程中发挥重要的作用,主要负责神经元动作电位的产生与传导[1]。
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电压依赖性钠离子通道(Voltage-gated sodium channels, VGSCs)在脑兴奋过程中发挥重要的作用,主要负责神经元动作电位的产生与传导[1]。
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1.2.1 作用于电压门控钠离子通道毒素 电压门控钠通道(voltage-gated sodium channels,VGSCs)是指在去极化电压诱导 下才能被激活的钠通道。许多天然的钠通道毒素,大多数都是电压门控型毒素。
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Furthermore, the external calcium was found to influx mainly through N-type calcium channels and voltage-gated sodium channels.
我们进一步用膜通道阻断剂验证,发现胞外钙的流入主要是通过N型钙通道和电压门控钠通道流入胞内的。
Conclusion The analgesic effect of IS was presumably caused by modulation of voltage-gated sodium channels in primary sensory neurons besides structure destruction of myelin sheath and axon membrane.
结论野木瓜注射液除影响髓鞘和轴突膜结构外还通过调制初级感觉神经元电压门控性钠通道,影响痛觉信息中枢传入产生镇痛作用。
Now, remember we talked about these last time, voltage-gated channels are channels that would allow the passage of sodium, in this case, but they can exist in two states, a closed state and an open state.
还记得我们上节课讨论过的吧,电压门控通道是,一种可以容许钠离子通过的通道,在这一例子中 电压门控通道有两种状态,关闭状态和开放状态
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