结论:NMS对小鼠急性脑缺血具有一定的保护作用。
Conclusion: NMS may have protective effect on the cerebral ischemia injury in mice.
第8天,除正常组外其余小鼠麻醉后,结扎双侧颈总动脉和迷走神经,造成小鼠急性脑缺血模型。
On the 8th day mice except in normal group were anesthetized and ligated bilateral common carotid artery and pneumogastric nerve so as to establish models of acute ischemia.
结果QN胶囊可延长缺氧小鼠和急性脑缺血小鼠的存活时间;
Results QN capsules could significantly prolong the survival time of hypoxic mice and the mice with acute cerebral ischemia.
结果表明,对小鼠抗脑缺氧、抗急性脑缺血及抗急性脑栓塞形成等均有显著的保护作用,其药效与腹腔注射尼莫地平溶液接近,显著优于灌胃给药。
Nimodipine liposomes could effectively protect the brain against damage, and were comparable to that after IP nimodipine injection but significantly better than that after ig administration.
结果表明,对小鼠抗脑缺氧、抗急性脑缺血及抗急性脑栓塞形成等均有显著的保护作用,其药效与腹腔注射尼莫地平溶液接近,显著优于灌胃给药。
Nimodipine liposomes could effectively protect the brain against damage, and were comparable to that after IP nimodipine injection but significantly better than that after ig administration.
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