肝脏药物转运体1B1基因多态性与他汀类药物致肌病有关;
The polymorphisms of liver drug transporter 1B1 genes are associated with myopathy induced by stating.
本文以风湿性疾病常用的治疗药物为主线,归纳了近年来影响药物疗效中有关药物代谢酶、药物转运体和药物作用靶点的基因组学研究进展。
The progress of pharmacogenomic research in the effects of drug treatment on rheumatic diseases could prevent adverse reactions, and provide reasonable guidance to clinical treatment.
与其它类型抗抑郁药物相比,抗抑郁药物物联合高效血清素转运体抑制剂与卒中风险增高相关。
Use of antidepressants with high inhibition of the serotonin transporter was associated with a greater risk for stroke than use of other types of antidepressants.
肠道转运体、肝脏药物代谢酶及肾脏在药物adme过程中发挥着重要作用。
Intestinal drug transporters, hepatic drug metabolic enzymes and the kidney play a very important role in the process of ADME.
在接受放射性药物123i - FP - CIT注射3小时后,患者进行了单光子发射断层扫描(SPECT)成像评估基线多巴胺转运体功能。
Three hours after receiving an injection of the radiopharmaceutical 123i-fp-cit, patients underwent single-photon emission tomography (SPECT) scanning to assess baseline dopamine transporter function.
研究者还发现,柚皮素能拮抗药物摄取的关键转运体,OATP1A2,它能使药物从小肠转运到血液中。
The team also found that naringin appeared to block a key drug uptake transporter, OATP1A2, which has a role in transporting drugs from the small intestine into the bloodstream.
药物代谢酶、转运体及药物作用靶点存在着的基因多态性与药物疗效和毒性的个体差异有很大关系。
The genetic polymorphism of drug metabolizing enzyme, transporter and target greatly influence the individual difference of drug efficiency and toxicity.
A BCG2是半ATP结合盒转运体。它可以转运内源性物质和人工合成的抗肿瘤药物等多种底物。
ABCG2 is a half ATP-binding cassette (ABC) transporter that facilitates efflux of a wide variety of substrates ranging from natural products to synthetic anticancer drugs.
A BCG2是半ATP结合盒转运体。它可以转运内源性物质和人工合成的抗肿瘤药物等多种底物。
ABCG2 is a half ATP-binding cassette (ABC) transporter that facilitates efflux of a wide variety of substrates ranging from natural products to synthetic anticancer drugs.
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