Since varenicline is only a partial agonist—not a full agonist—at the alpha4beta2 receptor site, it performs differently in smokers and nonsmokers, she said.
对alpha4beta2受体来说，既然伐伦克林仅是部分激动剂--不是完全激动剂，它对吸烟者和非吸烟者的作用是不同的，她说。
Inverse agonist is a new type of classification.
反向激动剂指一种新分类概念。
Greater leukocyte reaction is induced by agonist in patient with asthma.
哮喘病人外周血白细胞受激动剂作用会产生更大的细胞反应。
BYETTA is the first FDA-approved GLP-1 receptor agonist for the treatment of type 2 diabetes.
百泌达是FDA批准的治疗2型糖尿病的首个GLP- 1受体激动剂药物。
A noncompetitive antagonist prevents the agonist from producing any effect at a given receptor site.
非竞争性拮抗剂可阻止激动剂在特定受体部位产生任何效应。
A noncompetitive antagonist prevents the agonist from producing any effect at a given receptor site...
非竞争性拮抗剂可阻止激动剂在特定受体部位产生任何效应。
BYDUREON and BYETTA belong to the glucagon-like peptide-1 (GLP-1) receptor agonist class of medications.
BYDUREON和百泌达(BYETTA)都属于胰高血糖素样肽(GLP - 1)受体激动剂类药物。
If you could get a clever leptin agonist molecule then there is of course huge potential for the treatment.
如果我们能够研发出“更聪明的药物”，比如瘦素受体激动剂，那么它肯定有巨大的治疗潜力。
Provided herein is a method of reversing or preventing a target cell's resistance to a death receptor agonist.
本文提供了反转或阻止靶细胞对死亡受体激动剂的抗性的方法。
Objective to observe the effect of excitatory amino acids receptor agonist on the onset of puberty in female rats.
目的研究兴奋性氨基酸受体激动剂对雌性大鼠青春期启动的影响。
Different form antagonist that blocks the effect of agonist, inverse agonist produces opposite effect to that of agonist.
与阻断激动剂效应的拮抗剂不同，反向激动剂产生的效应与激动剂相反。
AIM: to investigate the role of protease-activated receptor-2 (PAR-2) agonist in the formation and pathogenesis of stress ulcer.
目的：探讨大鼠蛋白酶激活受体- 2在应激性溃疡中的作用。
With study development of CCK receptor antagonist and agonist, people have deep understanding about CCK's physiological function.
CCK受体激动剂与拮抗剂的研究深入，促进了人们对CCK生理功能的深入认识。
Yichongjing is a novel insecticide, it is highly specific to lepidopterous insects and ACTS as a safe and selective ecdysone agonist.
抑虫肼是一种新颖昆虫蜕皮加速剂。它对鳞翅目害虫高度有效，是一种既安全又有选择性的蜕皮激素杀虫剂。
CONCLUSION Geniposide has the similar function as the agonist for GLP-1 receptor, including neurotrophic and neuroprotective effects.
结论京尼平苷具有与GLP - 1受体激动剂类似的神经营养和神经保护功能。
The invention relates to a multi- peptide agonist vitro screening method of the glucagon peptide-1 receptor and the screened multi- peptide.
本发明涉及胰高血糖素样肽-1受体的多肽类激动剂的体外筛选方法及筛选得到的 多肽。
Objective: to study the protecting effect of delayed preconditioning with A1 selective adenosine receptor agonist in donor heart preservation.
目的：探讨腺苷a1受体激动剂延迟预处理对大鼠心脏的保护效果。
To investigate the role of cytokines, we blocked cytokine release by using GTS-21, a selective agonist of the 7 nicotinic acetylcholine receptor.
为研究细胞因子的作用，我们使用GTS - 21(烟碱乙酰胆碱受体7的一种选择性激动剂)来阻断细胞因子的释放。
VPAC1 agonist displayed more effective effects than VIP on body weight, plasma glucose, glucose tolerance, plasma insulin, the weight of viscera.
而VPAC1激动剂在体重、血糖、糖耐量、胰岛素浓度及内脏净重等方面的治疗效果更为明显。
OBJECTIVE To investigate the protective effects of M3 receptor agonist pilocarpine on myocardial ischemia-reperfusion injury in isolated rat hearts.
目的研究M3受体激动剂毛果芸香碱对离体大鼠心肌缺血再灌注损伤的保护作用。
The secretion of progesterone was assayed by rad ioimmunoassay. The results showed that GABA stimulated progesterone secretion , GABA agonist muscimol had the same effect.
结果显示GABA促进大鼠黄体化颗粒细胞孕酮分泌，蝇覃醇有同样作用。
Administration of the RXR agonist 9-cis-retinoic acid to demyelinated cerebellar slice cultures and to aged rats after demyelination caused an increase in remyelinated axons.
向脱髓鞘的小脑切片培养物和脱髓鞘后的衰老大鼠给予RXR激动剂9-顺式-视黄酸能够增加轴突髓鞘再生。
Conclusions The R PIA, a stable specific adenosine A 1receptor agonist, may mediate delayed myocardial preconditioning which reduces significantly the infarct size of myocardium in rats.
结论RPIA可使大鼠在体心脏产生延迟预适应（显著降低心肌梗死范围） ；
The pharmaceutical composition useful in this invention comprises a P2Y receptor agonist with enhanced resistance to extracellular hydrolysis, such as dinucleoside polyphosphate compounds.
所述对本发明有效的药物组合物含有对胞外水解有增强抗性的P2Y受体激动药，如二核苷酸多磷酸化合物。
Objective To investigate the possible neuroprotective effect of dopamine(DA) receptor agonist R-apomorphine(R-APO) on the 6-hydroxydopamine(6-OHDA)-induced rat model of Parkinson's disease.
目的探讨阿扑吗啡是否对6-羟基多巴胺毁损纹状体帕金森病鼠模型有神经保护作用。
The present invention provides for novel compounds of Formula (I) and pharmaceutically acceptable salts and co-crystals thereof which have glucagon receptor antagonist or inverse agonist activity.
本发明提供了具有胰高血糖素受体拮抗剂活性或反向激动剂活性的、新颖的式i化合物及其药学上可接受的盐和共晶体。
The present invention provides for novel compounds of Formula (I) and pharmaceutically acceptable salts and co-crystals thereof which have glucagon receptor antagonist or inverse agonist activity.
本发明提供了具有胰高血糖素受体拮抗剂活性或反向激动剂活性的、新颖的式i化合物及其药学上可接受的盐和共晶体。
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