Seattle went ahead on Ackley's RBI double in the second off Andy Pettitte (4-3) but gave up a run-scoring double to rookie David Adams in the bottom half.
Seattle also got runs on Dustin Ackley's RBI double in the second and Michael Morse's sixth-inning homer off former Mariners pitcher Shawn Kelley, a drive that bounced off the divider between Monument Park and the Yankees bullpen in right-center for his 10th homer this season.