The study points to human activity as the cause, because of the suddenness of the shift in temperature which appears to be out of whack with long-term trends.

WSJ: Earth Hotter Now Than Most of Past 11,000 Years

With used-car values already out of whack, shoppers need to be extra cautious to avoid compounding an already unfavorable financial situation by selecting a more problematic model that will require costly out-of-warranty repair work.

MSN: Used-car clunkers to avoid

And if the balance stays out of whack--if every company wants to be private and none public--that will be bad for the future of American democratic capitalism.

FORBES: Magazine Article

In financial services, the ability to drill down into data and find something that is out of whack on a mobile device and then send an email will be prized.

FORBES: arcplan Makes Chaos Comprehensible

If it's not perimenopause, it could be stress, severe weight loss, or extreme weight gain, all of which can knock your hormones out of whack.

CNN: Your period: What's normal, what's not, what to do