In order to restore the eye to its original shape, those with advanced keratoconus generally undergo a cornea transplant, a procedure with a long recovery time that demands the patient refrain from physically stressing the eyes for months.

FORBES: A New Hope for Those With Down Syndrome...And a Rare Eye Disease

The eye begins to form a cone shape, distorting vision along the way.

FORBES: A New Hope for Those With Down Syndrome...And a Rare Eye Disease

In homage to the Surrealists, Louboutin once created a pair of pumps with a hydrodynamic shape, a bulging eye above the pinkie toe, and tessellating rows of black and gold scales the foot as a fish.

NEWYORKER: Sole Mate

But the philosophy of applying an artisan's eye to detail and precision continued to shape its fashion output, on the runways of Milan and in stores worldwide as the brand went global.

NPR: Patriarch Of Fashion Brand Missoni Dies In Italy

The collection was formed over 50 years, with an eye "for the perfect line, profile and shape, in a magical way that cannot be improved upon, " says Charles Cator, chairman of Christie's furniture department.

WSJ: Collecting: Treasures With History

To the outside eye of the biographer is added another complication: these characters are chameleons and shape-shifters, deliberately out to lose themselves.

ECONOMIST: Literary biography