Over the years, Boeing has probably accumulated more data on the fatigue life of airframes than any other plane-maker.

ECONOMIST: Aircraft fatigue

The aim, as always, is to ensure that unpredictable factors do not reduce the fatigue life of a structure to less than that required.

ECONOMIST: Aircraft fatigue

Impurities in its material affect the fatigue life.

ECONOMIST: Aircraft fatigue

To my chagrin, the list was pretty long because at this point in my life conference fatigue is my default setting.

FORBES: Connect

In my case, because titanium does not rust or fatigue appreciably, its useful life is until I die.

FORBES: Why You Need a Custom Road Bike

So you find yourself facing the challenges alone -- the pain that literally doubles you over without warning: nausea, life-threatening bowel obstructions, incontinence, dehydration, intravenous feeding, fatigue and depression.

CNN: Living with Crohn's disease: 'Today I will fight again'

"On three occasions in my life, I have voluntarily gone into hospitals as result of nervous exhaustion and fatigue, " Eagleton said at the time.

NPR: To Tell or Not? Disclosing Candidate Health Issues