The long-term hope is to treat patients with some sort of stem cell that could turn into beating heartmuscle and replace dead cardiac tissue with fully functioning new cells.
They found that the stem cells produced growth factors that traveled to the heart, in addition to stimulating the muscle itself to make growth factors that also improved cardiac function.
He has managed to reprogram mouse connective-tissue cells so that they develop into cardiacmuscle cells, and has tested them in the hearts of mice that have had heart attacks.