Sanath Jayasuriya plucked out Martin van Jaarsveld and nightwatchman Nicky Boje in one over to reduce South Africa to 116-3 in reply to the hosts' 470.
Astle, 32, struck 103 to give the tourists a slim chance of saving the match as they finished day three on 282-8 in reply to India's 500-5 declared.
It saw Northants to 92-1 off seven overs in reply to Somerset's 200-7 when the weather forced a premature end.
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After the Red Rose County declared on 489-5 in reply to the Tykes' 181 all out, Yorkshire began the final day on 71-2 in the second innings, 237 behind.
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In division one Wellington hung on for a draw on 119-9 in reply to Cannock's 160 as Adam Byram took four wickets.
But Paul Hoffmann bowled an economical spell to claim 2-24 off his 10 overs as the visitors slumped to 28-3 in reply.
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The Kiwis made 275 in their first innings in reply to South Africa's 474-9 declared.
Edinburgh Reivers produced a storming second-half performance, scoring 30 points without reply, to avenge their defeat by Neath in the Welsh-Scottish League earlier in the season.
Elsewhere in Division Three, Newport were bowled out for just 121 in reply to Eastnor's 261-9.
But bad weather returned with the hosts 76-1 in reply, to leave the match abandoned with no result.
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Australia are 220-5 in reply to England's 260, with Mike Hussey on 81.
Their determination and astute running between the wickets enabled them to set a competitive total of 220-6, then maintained a tight line and length to restrict their rivals to 205-9 in reply.
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FORBES: Eight Steps to an Impressive Off-the-Cuff Reply at Work
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But, having looked in control in reply on 159-3, Ian Bell's crucial demise for 65 saw the Bears slump to 212-9.
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John Blain and Craig Wright were soon among the wickets as the Dutch slumped to 22-3 in reply.
And although rain again intervened, the hosts were reduced to 164-6 in reply, 115 short of avoiding the follow-on.
Javed Omar carried the hosts to 82-3 in reply, with an unbeaten 44 after Daniel Vettori took two wickets.
BBC: SPORT | Cricket | Other International | Kiwis build on Fleming double ton
Simon Katich (92) and Michael Hussey (45) then added an unbroken 115 to take the Aussies to 189-2 in their reply.
India were in trouble from the start in reply, Zoysa tempting Sachin Tendulkar into hoisting one to Jayantha in the fourth over - and he claimed another when Parthiv Patel was caught by Sangakkara.
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In reply, the home side struggled to 139-9, Alan Chapman scored 53 to help save the game.
Jarrod Cunningham slotted two penalties in reply to level the scores at 6-6.
Zimbabwe, who rested skipper Heath Streak and Waddington Mwayenga from the Somerset match, slumped to 19-2 early in their reply.
In an instant-response, social media era in which the slightest provocation and merits a reply, it doesn't react to campaigns or even polite queries.
On Sunday, Chelsea will look to overcome Brentford in their fourth-round reply while Manchester City and Wigan face Leeds United and Huddersfield respectively in the fifth round.
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CNN: ASIANOW - TIME Asia | Asia Buzz: It Still Isn't Very There Here
The USA crumbled to 110-8 at the close in reply as Davison returned figures of 6-49 from 11 overs of off-spin.
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