Referral to a lipid specialist is also very appropriate in such patients.
Also unclear, according to Prediman K. Shah, a lipid expert at Cedars Sinai Hospital, is whether the drug will reverse plaque build-up as Esperion's drug did.
However, they recommend screening adults for high triglycerides as part of a fasting lipid panel.
To investigate what impact a forced switch to a low-lipid regime might have on the development of red-legged kittiwakes, the Kitaysky lab designed experiments to explore the effects of various diets.
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The scientists found a way to chemically remove the lipid fats that normally make brain tissue opaque, in effect turning any postmortem brain specimen into a picture window that reveals its internal structure.
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His comments have stemmed from the press release from Sanofi and Regeneron outlining their extensive Phase 3 program for their novel lipid lowering agent , REGN27, a PCSK9 inhibitor which is the most advanced agent in this highly competitive field.
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And he is working with Nissen to see if a medical device made by Lipid Sciences can clean the primates' pipes by increasing good cholesterol.
But the right circumstances depend on what is happening in the lipid layers because, by itself, a single gramicidin channel is not long enough to span the membrane and thus let any sodium ions through.
Sometimes the challenge is to match a Piccolo application to a medical specialty--oncologists, say, who need lots of lab work before administering chemotherapy, or cardiologists, who might buy a machine for its quick lipid readings.
Physicians usually prescribe a drug based on the underlying lipid abnormality.
The randomized, double-blind, placebo-controlled, multi-center trial enrolled 51 patients age 12 to 53 years, including 7 patients age 12 to 16 years, who were maintaining a regimen of maximally-tolerated lipid lowering medications.
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It is not every day that an international consortium of concerned lipid scientists gets upset, but just such a group, rallied by Jack Winkler of the Nutrition Policy Unit at London Metropolitan University, is on the warpath.
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The U.S. Food and Drug Administration today approved Kynamro (mipomersen sodium) injection as an addition to lipid-lowering medications and diet to treat patients with a rare type of high cholesterol called homozygous familial hypercholesterolemia (HoFH).
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Similarly, lipid lowering drugs were approved with only LDL lowering properties and a year of patient exposure.
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According to a VG Energy press release, the technique increased production of extractable lipid, or fat, by at least 300 percent when applied in the lab.
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KYNAMRO, given as a 200 mg weekly subcutaneous injection, has been approved as an adjunct to lipid-lowering medications and diet to reduce low density lipoprotein-cholesterol (LDL-C), apolipoprotein B (Apo B), total cholesterol (TC), and non-high density lipoprotein-cholesterol (non HDL-C) in patients with homozygous familial hypercholesterolemia (HoFH).
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James Howard, director of the Lipid Clinic at MedStar Washington Hospital Center in Washington, DC, says the new changes are a real step forward.
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