Effects of the traditional Chinese herbal medicine Yi-Gan San for cholinesterase inhibitor-resistant visual hallucinations and neuropsychiatric symptoms in patients with dementia with Lewy bodies.
The anti-spasticity medication (brand names Kemstro and Lioresal) was earlier touted as an antidote for cocaine abusers in a study by the UCLA Neuropsychiatric Institute.
We expect initial uptake to be in patients who experience neuropsychiatric side effects on Atripla and are seeking an alternative or those who have already switched off Atripla to another therapy.
Further, the benefits in reduction of neuropsychiatric side effects of Atripla came at the cost of more GI side effects, although the higher rates of nausea were primarily of lower grade.