He added that he had not changed his mind that the vote was a once-in-a-generation opportunity.

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Doha represents a once-in-a-generation opportunity to help millions in the developing world rise from poverty and despair.

NPR: President Bush's Remarks on the World Agenda

Mr Miliband said the Leveson report provided a "once-in-a-generation opportunity for real change" and backed an all-party approach.

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Worse yet, by their petty parsimony, they risk squandering a once-in-a-generation opportunity to do very well strategically by doing good.

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We face a once-in-a-generation opportunity to empower people in our changing world.

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His instinct is to be supportive because of the chilling effect of the crisis on the UK. But to many of his supporters this is a once-in-a-generation opportunity to win back some powers from Brussels.

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