From studies of pregnant sharks, it emerged that there may be an "optimum size range" for the mothers.

BBC: Shark mums 'invest' in newborns

He is creating computer simulations to model the liver, so optimum channel size, flow rate and density of cells can be calculated as accurately as possible, before the artificial liver is constructed in the laboratory.

BBC: NEWS | Health | Glass liver may aid disease fight

In the absence of size, Benioff is hustling to convince the world that Salesforce's technology is the optimum base--or platform, a.k.a.

FORBES: On The Cover/Top Stories