Researchers in Pennsylvania conducted experiments with mice bred to develop neurological symptoms associated with abnormal a-syn after about 12 months.
Parkinson's disease is characterized by clumps of abnormal brain proteins called Lewy bodies of which a-synuclein (a-syn) protein is the principal component.
After 90 days, a-syn proteins resembling Lewy bodies were widely distributed throughout the central nervous system of the first group, suggesting a-syn from diseased tissues had a highly potent seeding effect, researchers said.