Magazines were one of the earliest mechanisms for social grouping, and before the onset of the digital age, publishers were very good at building and monetizing highly valuable networks of similar people built around different content verticals.
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The company was positioned perfectly for the onset of the Internet Age.
Still, "most of the family history that we're collecting is just the presence or the absence of heart disease, not the age of onset or the type of disease, " says Dr. Arnett, who wasn't involved in the latest research.
The handful of dragons, the illusory sunset over Anor Londo, the last molten gasps of the Age of Fire, the onset of darkness and the flight of hope from the world these are all things going on in the original Dark Souls.
"This is the first time anyone has shown that a single parkin mutation can lower the age of onset, " said Dr James Gusella, study leader and director of the Massachusetts General Hospital Center for Human Genetic Research.
Professor Peter Clayton, a paediatric endocrinologist at the University of Manchester, told the BBC News website it was still unclear what factors might be driving a reduction in the age of onset of puberty.
Anxiety disorders emerge early in life: The median age of onset is 11, according to the study.
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Victoria Copas, one of the paper's authors, says a Spanish study found that social interaction delayed the onset of neurological diseases associated with old age.
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Merely getting older doesn't make mental health problems more likely to occur, Rabins said, noting that middle age is the most common time for onset of depression.
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Where both twins had the disease, there was an average of 3.66 years difference in age at onset between 25 sets of identical twins, and 8.12 years difference between 20 sets of fraternal (dizygotic) twins, suggesting genes had a role in determining when Alzheimer's was seen.
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