As polls have shown, opposition to the war effort has also begun to gnaw at the conservative base.

NPR: Sheehan Magnifies Fissures on Iraq

It's already starting to gnaw at them.

NPR: This Week in Washington: Iraq Debate, Intel Estimate

Many pharmaceutical companies are struggling as expiring patents allow cheap generic drugs to gnaw away at their sales.

FORBES: Magazine Article

At its most extreme, people like Masellis will do just about anything to satisfy a hunger that can gnaw at the will just as hard as an addiction to alcohol, drugs or gambling.

FORBES: They've Gotta Have It

The implications of Arthur's work, however, suggest something more elemental is at play: Our accomplishment and our happiness are tied up with our very human desire to find and gnaw over the missing thing, the problem and the need.

FORBES: Commentary