At most a couple of thousand patients worldwide have the inherited disorder, which causes recurring fevers, rashes, joint pain and kidney damage.

FORBES: Magazine Article

For instance, in the past several years, scientists have come to understand that a particular gene signature--a pattern of genes that are turned on and off--can be a powerful contributor to the disease Lupus, which causes swollen joints, fevers and rashes.

FORBES: Genentech's Next Act