这些研究人员将肽(蛋白质片段)化合物作为研究重点,该化合物为多发性骨髓瘤细胞所独有,对于这种细胞的生存至关重要。
The researchers deployed a combination of peptides—small pieces of protein—that are known to be specific to multiple myeloma cells and are important for their survival.
多发性骨髓瘤是一种血浆细胞癌症。
MultipleMyeloma研究基金会资助了一家小型生物科技企业的研究,发现了一种很有前途的新药,能够治疗多发性骨髓瘤,一种骨头中原生质细胞的癌症。
Research funded by the multiple myeloma Re — search Foundation at a small biotech led to a promising new drug for multiple myeloma, a cancer of plasma cells in bones.
MultipleMyeloma研究基金会资助了一家小型生物科技企业的研究,发现了一种很有前途的新药,能够治疗多发性骨髓瘤,一种骨头中原生质细胞的癌症。
Research funded by the Multiple MyelomaRe--search Foundation at a small biotech led to a promising new drug formultiple myeloma, a cancer of plasma cells in bones.
低倍镜显示多发性骨髓瘤异常浆细胞弥漫浸润骨髓。
At low power, the abnormal plasma cells of multiple myeloma fill the marrow.
目的:探讨多发性骨髓瘤(MM)的主要临床特点以及骨髓细胞形态学在MM诊断中的作用。
Objective To investigate the clinical features in patients with multiple myeloma (MM) and the significance of bone marrow cell morphology in MM diagnosis.
“我们已经知道,在B细胞过度表达或突变的NIK和TRAF3分子是与人类多发性骨髓瘤相关,”麦凯教授说。
"We already know that the over-expression or mutation of molecules known as NIK and TRAF3 in B cells is associated with human multiple myeloma," said Professor Mackay.
还有,当大多数人听到的诊断早幼粒细胞白血病,淋巴瘤或多发性骨髓瘤,他们的反应是惊愕,恐惧和难以置信。
Still, when most people hear a diagnosis of leukemia, lymphoma or myeloma they respond with shock, fear and disbelief.
中倍镜显示多发性骨髓瘤的浆细胞与正常浆细胞很相似,但分化较差。
At medium power, the plasma cells of multiple myeloma here are very similar to normal plasma cells, but they may also be poorly differentiated.
目的观察供体白细胞输注(DL I)治疗急慢性白血病和多发性骨髓瘤的疗效和安全性。
Objective To observe the therapeutic efficacy and safety of donor leukocyte infusion (DLI) in acute, chronic leukemia and multiple myeloma.
从这个病例中得到的教训是,在器官移植后的严重免疫抑制状况下,暂时性血细胞恶液质可以有类似多发性骨髓瘤样的表现。
The lesson to be learned from the present case is that a transient plasma cell dyscrasia may present like multiple myeloma in the setting of heavy immunosuppression after organ transplantation.
鉴于这个目的,他通过统计学方法对一群多发性骨髓瘤病人的细胞发生的变化进行了分析。
For this purpose, he has analyzed, by means of statistical methods, the cytogenetic changes in a group of patients with MM.
目的研究多发性骨髓瘤(MM)细胞脑源性神经营养因子(BDNF)的表达水平及其与MM细胞诱导的血管新生的关系。
Objective To investigate the expression of brain-derived neurotrophic factor (BDNF) in multiple myeloma (MM) cells and the correlation between BDNF and MM angiogenesis.
方法采用三色免疫荧光直接标记法及多参数流式细胞术分析13例多发性骨髓瘤的免疫表型。
Methods Three-colour direct immunofluorescence staining and multiparameter flow cytometry were used for analysis of 13 samples of immunophenotyping of multiple myeloma patients.
目的:探讨组蛋白去乙酰化酶抑制剂MS- 275诱导人多发性骨髓瘤细胞株u266凋亡的分子机制。
OBJECTIVE: to investigate the molecular mechanisms of histone deacetylase inhibitor MS-275 on apoptosis of human myeloma U266 cell line.
结论:骨髓浆细胞增殖及尿链蛋白产生可能是多发性骨髓瘤肾脏损害的主要原因。
Conclusion: Proliferation of bone marrow plasmacyte and the quantity or urine Bence-Jones protein are main causes of kidney lesion in multiple myeloma.
孤立性的硬膜浆细胞瘤是不常见的,而多发性骨髓瘤相关的浆细胞瘤相对更常见些。
Plasmacytomas of the dura are uncommon plasma cell tumors that may occur as a solitary neoplasm or, more commonly, in association with multiple myeloma.
结果:对各类型白血病、多发性骨髓瘤、骨髓转移癌、部分恶性组织细胞病及疟疾可确诊。
Results: Various types of leukemia, multiple myeloma, malignant histiocytosis, bone marrow metastatic tumors and malaria can be identified by bone marrow examination.
并探讨多发性骨髓瘤的细胞学诊断问题,指出骨髓瘤细胞质与量变化的特点及其临床意义。
The cytological diagnosis of multiple myeloma was discussed, the characteristics of qualitative and quantitative changes of the myeloma cells and also their clinical significance were suggested.
目的:研究多发性骨髓瘤(MM)患者肿瘤冻融物致敏的树突细胞(DC)能否诱导特异性细胞毒t淋巴细胞(CTL)反应。
Objective: to explore the specific cytotoxic t lymphocyte (CTL) response induced by DC pulsed with tumor lysates from multiple myeloma (MM) patients.
在多发性骨髓瘤(MM)的发病机制中,白细胞介素- 6 (I L - 6)是肿瘤细胞生长和生存的一个重要因素。
In multiple myeloma (MM) pathogenesis, IL-6 has been identified as an essential growth and survival factor.
目的:探讨采用自体外周血干细胞移植(简称ASCT)治疗老年多发性骨髓瘤(简称MM)疗效及安全性。
Objective: to observe the efficacy and security of autologous peripheral stem cell transplantation (ASCT) for elderly multiple myeloma (MM).
多发性骨髓瘤(MM)是一种起源于B细胞系并能够产生单克隆免疫球蛋白的恶性增生性疾病。
Multiple myeloma(MM) is a kind of malignant hyperplastic diseases, which is origined from B cell line and can produce monoclonal immunoglobulin.
在进行化疗的,多种小鼠肿瘤模型和多发性骨髓瘤患者中,研究者均观察到MPR在肿瘤细胞表面的积累。
MPR accumulation on the tumor cell surface during chemotherapy was observed in different mouse tumor models and in patients with multiple myeloma.
多发性骨髓瘤是一种浆细胞恶性增生,单克隆免疫球蛋白合成异常的恶性疾病。
Multiple myeloma is a vicious monoclonal B - cell disease with plasmacyte proliferating slowly.
目的研究组蛋白去乙酰化酶抑制剂MS275对人多发性骨髓瘤细胞U266增殖的影响。
ObjectiveTo investigate the antitumor effect of MS275, a histone deacetylase inhibitor, on growth of the human myeloma cell line U266.
多发性骨髓瘤骨髓涂片可见很多浆细胞,核偏位,核周围胞浆透亮清晰。
Here is a smear of bone marrow aspirate from a patient with multiple myeloma. Note that there are numerous plasma cells with eccentric nuclei and a perinuclear halo of clearer cytoplasm.
确诊病例包括:孤立性浆细胞瘤1例,转移癌24例,结核5例,多发性骨髓瘤4例,恶性淋巴瘤2例,骨感染3例,3例误诊。
The confirmed cases included: 1 case of solitary plasmacytoma, 24 metastasis lesions, 5 tuberculosis, 4 multiple myeloma, 2 malignant lymphoma and 3 bony infection. 3 cases were misdiagnosed.
它对血细胞的毒性作用已得到很好地记载,而且已知它导致不同类型的白血病、多发性骨髓瘤和非霍奇金淋巴瘤。
Its toxic effects on blood cells are well documented and it's known to cause different kinds of leukaemia, multiple myeloma and non-Hodgkin lymphoma.
在低倍镜下,异常浆细胞填满了多发性骨髓瘤病人的骨髓。
At low power, the abnormal plasma cells of multiple myeloma fill the marrow.
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