研究结果显示,MTD平台运行情况稳定,适合多靶点药物方面的研究。
These studies demonstrated that the MTD platform is stable and suitable for multiple target researches.
多靶点药物可以同时调节疾病网络系统中的多个环节,不易产生抗药性,对各靶点的作用产生协同效应,达到最佳的治疗效果。
Multi- target therapeutics which regulates multiple nodes of the disease network simultaneously shows synergistic effect, is unlikely to induce resistance and provides optimal clinical use.
方法查阅2例患者的住院病史和门诊病历,分析原发肿瘤分期、影像学表现、多靶点药物治疗时间、毒副反应、病灶对药物的反应、手术时机、术中所见、病理报告和预后。
Methods Medical records of these 2 patients were reviewed to find the duration of target therapy, toxicity, response of tumor, surgical approach, intraoperative findings, and pathology analysis.
培美曲塞是一种多靶点的抗代谢类药物,目前已经在70余个国家批准上市,用于治疗恶性胸膜间皮瘤和非小细胞肺癌。
Pemetrexed is a multitargeted antimetabolite that has shown activity in malignant pleural mesothelioma and NSCLC, which has been approved in more than 70 countries.
VS及多离子通道的病变可作为药物治疗病变心脏心律失常的新靶点。
The VS and multiple ion channel disorder are provided as new targets to treat cardiac arrhythmias in a diseased heart.
多靶点是抗肿瘤药物引起不良反应的主要原因之一,开发单一靶点药物是提高药物专属性的一种有效方法。
Multi-target is one of the key reasons of side-effects induced by anti tumor drugs. So exploiting single-target drugs is an effective method of enhancing drug specificity.
由于目前的药物起效慢和不良反应多,临床疗效仍不满意,多靶点、多系统共同作用类药物已成为新的研究方向。
They still can not meet clinical needs with respect to both efficacy and side effects. A diversity of multi-target strategies are proposed for the future generation of successful antidepressants.
由于目前的药物起效慢和不良反应多,临床疗效仍不满意,多靶点、多系统共同作用类药物已成为新的研究方向。
They still can not meet clinical needs with respect to both efficacy and side effects. A diversity of multi-target strategies are proposed for the future generation of successful antidepressants.
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