以溴戊烷、溴己烷、1，2-二溴乙烷和亚磷酸三甲酯为原料，分别合成了戊基、己基、溴乙基取代的三种膦酸二甲酯化合物。
In this paper, three alkyl substituted dimethyl phosphonates have been synthesized by trimethyl phosphite with 1-Bromopentane, 1-Bromohexane and 1,2-Dibromoethane.
西司他丁钠的合成以乙酰乙酸乙酯和1-溴-5-氯戊烷为原料，经活性亚甲基烃化、成肟和水解3步反应得7-氯-2-氧庚酸乙酯；
The synthesis of Cilastatin sodium started from ethyl acetoacetate and 1-bromo-5-chloropentane, through 3 steps to produce ethyl 7-chloro-2-oxoheptanoate;
西司他丁钠的合成以乙酰乙酸乙酯和1-溴-5-氯戊烷为原料，经活性亚甲基烃化、成肟和水解3步反应得7-氯-2-氧庚酸乙酯；
The synthesis of Cilastatin sodium started from ethyl acetoacetate and 1-bromo-5-chloropentane, through 3 steps to produce ethyl 7-chloro-2-oxoheptanoate;
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